UMA ÚNICA GRANDE DOSE DE VITAMINA D PODE SER USADA COMO MEIO DE PREVENÇÃO E TRATAMENTO DA DOENÇA CORONAVIRUS 2019 * A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment | Drug Design, Development and Therapy


A Single Large Dose of Vitamin D Could be Used as
a Means of Coronavirus Disease 2019 Prevention
and Treatment

“(…) Vitamin D Administration is Convenient and

“(…) Vitamin D is a lipid-soluble vitamin, and can be administered
as a draught. From our clinical experience in patients with Vit D deficiency or insufficiency, a single dose of 300,000 IU (in one ampulla) is safe. Four weeks after the administration, the serum 25(OH)D concentration can be elevated to the level of about 60 ng/mL, and all the patients have normal blood calcium levels. Vit D supplementation is very safe and Vit D toxicity is a rare event caused by ingestion of excessively high
amounts of Vit D
. Most studies in children and adults have suggested that the blood levels need to be above 150 ng/mL before there is any concern. Therefore, an upper level of 100 ng/mL provides a safety margin in reducing risk of hypercalcemia. [12] The cases of Vit D toxicity accompanied by various toxic symptoms have serum 25(OH)D concentrations ranging from 213 to >640 ng/mL (533 to >1600 nmol/L).[36] To ensure safety, testing the blood calcium and 25(OH) D levels two to four weeks after taking Vit D is needed, but in most cases it is not always necessary. (…)”

Department of Endocrinology and
Metabolism, Peking University Third
Hospital, Beijing 100191, People’s
Republic of China

This article was published in the following Dove Press journal:
Drug Design, Development and Therapy – BIBLIOGRAFIA NO FINAL


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